Reigning champions Liverpool have been drawn against Athletico Madrid, while Manchester City will face Real Madrid in the first knockout round of this season’s UEFA Champions League.
In other exciting ties, Chelsea take on Bayern Munich in a repeat of the 2012 final while Tottenham face RB Leipzig in a tie the neutrals will love.
Elsewhere, 2013 finalists and 1997 winners Borussia Dortmund will play Paris St-Germain while take on Napoli take on the might of five time winners Barcelona.
The first leg games will be played on 18, 19, 25 and 26 February with the return matches on 10, 11, 17 and 18 March.
This season’s final will be played at the Ataturk Stadium in Istanbul on 30 May 2020.
Last-16 draw in full
Borussia Dortmund v Paris St-Germain
Real Madrid v Manchester City
Atalanta v Valencia
Atletico Madrid v Liverpool
Chelseav Bayern Munich
Lyon v Juventus
Tottenhamv RB Leipzig
Napoli v Barcelona.